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    With the suspension of Cincinnati Reds pitcher Edinson Volquez for performance enhancing drug use and a swirl of rumors that the agent involved was clomiphene (also known as Clomid,) I thought it timely to write about how clomiphene works and how it’s used. From what I read on the internets, there is an enormous amount of misinformation floating around out there. To understand how clomiphene works, you need to know how the pituitary controls the making of testosterone in the testis. Testosterone is made by Leydig cells in the testis, which I explained in my last post. The pituitary releases a hormone called luteinizing hormone (“LH”) that stimulates the Leydig cells to make testosterone. Testosterone is converted to the female hormone estrogen, (which I also explained in my last post,) and estrogen tells the pituitary to stop making more LH. This kind of negative feedback system is common when it comes to how hormones work. As the room gets warmer, the thermostat sends less electricity to the heater. I have been getting an awful lot of questions on Post Cycle Therapy (PCT) lately, so this article was much needed. I will explain everything I can about PCT to the best of MY KNOWLEDGE. This has been strictly based on my own experience and research, but maybe I can explain it in a way some of you can understand. The first thing I want you to know is there are different types of PCT I would run, PCT for a heavy cycle and PCT for a moderate or low dose cycle. Most of my cycles are low doses or moderate at best, and being that I'm on test replacement anyways, the way I do things now is a little different than the way I used to. Without getting into too much detail, the way I do things now is strictly HCG periodically and an aromatase inhibitor during cycle. Using an AI is a HUGE, HUGE, HUGE addition to a cycle and makes a major difference in how you look on cycle.

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