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    Retin-A (Tretinoin) is a topical (applied to the skin) form of Vitamin A that helps the skin renew itself. The Retin-A brand of tretinoin is used to treat acne. The Renova brand of tretinoin is used to reduce the appearance of fine wrinkles and mottled skin discoloration, and to make rough facial skin feel smoother. Tretinoin helps acne by causing the skin’s outer layer to grow more quickly and be replaced with new skin cells, which helps to reduce the formation of blackheads, whiteheads, and other acne lesions. It may take up to 2 to 4 weeks to see improvement in your acne and the full effect of the medication may not be seen until 6 to 12 weeks. We currently have the brand cream from India called Retino-A manufactured by Janssen-Cilag, the brand gel from Canada manufactured by Johnson & Johnson and the generic gel from India called A-Ret. Retin A comes in three different strengths and forms: a micro gel (0.1 %/20 gm, 0.04 %/20 gm, 0.04 %/45 gm), and a cream (0.025 %/20 gm/0.05 %/20 gm). Our Retinol Products There is no conclusive research that suggests that that AHA or BHA exfoliants reduce the effectiveness or is incompatible with Retinol when used together in a skin care routine. The confusion about using Retinol with AHA or BHA products has to do with concern over the exfoliant’s acidity lowering the skin’s p H, and by doing so, disrupting the Retinol’s ability to work its anti-aging, skin-smoothing magic. The reasoning behind this claim is that if the p H of skin is below the typical 5.5 to 6, an enzyme in your skin won’t be able to convert Retinol into its active form – Retinoic Acid, to be used by skin. This is based on the assumption that these acidic exfoliant ingredients lower the p H of skin, thus destabilizing the Retinol and/or deactivating the enzyme in skin that converts Retinol to its active form. The sole study which claimed this was only to compare how animal and human skin metabolize the form of vitamin A naturally present in skin, not about how topical Vitamin A benefits or functions in skin. Its conclusions were not intended to be used to make decisions about skincare. Retinol even remains stable in low-p H formulations. It’s worth noting that no research has replicated the p H limitations of the study.

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